Research

As a PhD student in the Toxicology Program at North Carolina State University my research interests include epigenetic and phenotypic changes affecting the placenta and fetal growth in response to environmental cadmium exposure. My research involves both in vivo and in vitro models to better understand the patterns of methylation establishment and maintenance of imprinted genes as well as their expression and association with placental efficiency during toxic insult.

Presentations:

My current poster highlights techniques used to analyze the effect of cadmium on the epigenome. By using a hybrid model of cadmium exposure we are able to determine the effects of metal exposure on growth factors such as Cdkn1c with parental specificity both at the transcript and genomic level.

Mark Simmers, Research Poster Presentation, 2020

Recent Presentations and Awards:

38thAnnual Meeting of the Mountain West Society of Toxicology, 2020, 1stPlace.
North Carolina Society of Toxicology Poster Competition at NIEHS, 2020
Genomic Imprinting – From Biology to Disease – International Virtual Meeting, 2020
Genetics and Mutagenesis Society of North Carolina – Fall Meeting, 2020

My recent presentation at the International Virtual Meeting on Genomic Imprinting:

Mark Simmers

Research Assistant, PhD Candidate 
Center for Human Health and the Environment
Department of Biological Sciences
North Carolina State University
Raleigh, NC 27695